Mangifera stigmasterol, friedelin, lupeol, etc. have also been reported

     Mangifera indica leaves has been
an important component of indigenous medical systems for over 4,000 years, and
the largest fruit tree discovered in India. The usage of Mangifera inidica leaves as a medicinal agent is dated
back to as early as 327 BCE. The presence
of some major groups of phytochemical constituents such ad saponins,
anthraquinones, terpenoids, etc. and therapeutically active components such as mangiferin, stigmasterol, friedelin, lupeol,
etc. have also been reported from
Mangifera indica leaves. There is a scarcity of scientific information in
support of their success, whilst the leaves have been traditionally used as the antibacterial and immunomodulatory
agent. Mangifera indica leaves are also used as an antibacterial agent in
Nigerian folk herbalism. To ascertain
whether or not there is a scientific basis for this use, the effect of the blood glucose level was assessed in normoglycaemic, glucose-induced
hyperglycaemic and streptozotocin (STZ)
induced diabetic rodents such as Rattus (rat). The aqueous extract given orally
did not modify the blood glucose levels in either normoglycaemic or STZ-induced
(streptozotocin) diabetic rodents specifically Rattus (rat).



Aqueous extracts of Mangifera indica leaves showed remarkable influence on reproductive functions,
wound regeneration and antidiabetic tasks. Alcoholic extracts of Mangifera
indica leaves have been found containing TNF- (Tumor necrosis factor), ILIB
expression and B-lactamase producing enteric
bacterial development.

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     Mangifera indica leaves are equipped with
a broad outer cuticle to avoid the loss of nutrients
and to prevent wetting when it’s
raining. Furthermore, Mangifera indica
leaves are found alternating on the plant stalk to exploit the light energy acquired from the sun. This is because of the
fact that Mangifera indica develops best when exposed to sunlight.