Bioethics is defined in McGonigle, D & Mastrian, K. G. (2018) , “as the ?study and formulation of healthcare ethics.” There are different thoughts ?about telling the truth in many cultures. Practitioner-patient ?communication relationship has changed extensively all over the world. ?In the past, the physician was the only one who can make the decision ?according to the patient diagnosis, disease, medication or the treatment ?plan. Sometimes physicians concealed and even not shared any ?information about the diagnosis or the treatment plan with the patient or ?his/her family. Nowadays, telling the truth to the patient is the ethical ?practice in many countries. According to McGonigle, D & Mastrian, K. ?G. (2018), “Autonomy is Right of individual to choose for her/himself.”?There was a 34 years old female, shows up in the ER with a small ?ulcer on her forehead. She has fallen on the ground after she felt some ?dizziness and she seems pale. The doctor ordered for her some blood ?sampling such as CBC to check for anemia and bone marrow biopsy. ?Once the doctor receives the result, he realized that the female patient ?had leukemia. In this case What is the ethical response? Is the ?physician having the right to tell the diagnosis to anybody else before ?informing the patient? What is the physician ethical response when the ?patient’s family ask the doctor not to reveal the diagnosis??Actually, the doctor tells the patient about her diagnosis because he ?wants to make a referral to the Oncologist to start a chemotherapy ?plan. Whereas, the patient asks the physician not to tell the diagnosis to ?her family. She thinks this bad news will make her family worried.?In conclusion, some people think that telling the truth to the patient ?specially about the malignant diseases will fear the patient and make ?him/her feel hopeless which is can easily affect the coping mechanism ?with the disease. Others believe that sharing information about the ?diagnosis will strengthen the trust relationship between the patient and ?the doctor. Moreover, will permit the patient to make decisions about ?his/her condition. Autonomy and Beneficence are closely related to tell ?the truth. Beneficence was described in McGonigle, D & Mastrian, K. ?G. (2018), “as actions performed that contribute to the welfare of ?others, to do good.” which is the good ethical response from the ?physician to tell the truth and let the patient participate in the decision-?making process. In addition, the patient was legally competent and she ?has the right to clearly state if she wants her family to know about her ?disease. However, the doctor should respect the patient’s wishes and ?believes.